Oral cholestyramine increases elimination of warfarin after overdose.

physiology of the pancreas graft, which is heterotopic and denervated, together with the immunosuppressive treatment and relatively impaired renal function might be responsible for minor differences in hormonal and metabolic patterns. Results comparable to ours have been described in non uraemic type I diabetic patients treated with artificial endocrine pancreas; continuous subcutaneous, intravenous, or intraperitoneal insulin infusions; and intensified conventional insulin treatments.31-35 Pancreas transplantation seems an ethical proposition in type I diabetic patients undergoing kidney transplantation for chronic renal failure and in whom immunosuppression is to be used. In these cases pancreas transplantation, when successful, leads to the restoration of normal metabolic homoeostasis without hormone replacement.